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I chose "D" because the author states, "If.....exist...may abound in the failed attempts...--in which case, scientists would be forced to question...."

E is correct.

D: "unsure"
E: "confident"

I thought "may" indicated the author's uncertainty about whether he or she thinks that RBOA would undermine the central tenet of science. But apparently the author is "sure" that it "would" do so.