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Is there any proper etiquette that you should inform schools where you won't be attending? Let's say you are ready to put down the deposit and you negotiated successfully to a point that meets your acceptable level of potential debt meaning your decision is made. Do you inform other schools so they can free up money/spots? Do you just ghost them until their deposit deadlines come and go?

Definitely withdraw if you're 100 percent sure. It's just good manners, I think, and as you said, frees up money and spots.